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PDF(1567 KB)
PDF(1567 KB)
持續性腹瀉的淋巴細胞性結腸炎1例
楊美娜1 LAI Ming Wei2
Lymphocytic Colitis in an Adolescent with Persistent Diarrhea-a Case Report
YEUNG Mei Na1, LAI Ming Wei2
NA
Microscopic colitis is a rare disease. The presentation is non[1]bloody chronic watery diarrhea. The colonoscopic appearance is characterized by normal or near-normal mucosa, but the histopathology has typical features, which are the gold standard for diagnosing microscope colitis[1]. According to the histological findings, there are two main subtypes of microscope colitis, lymphocytic colitis (with ≥20 intraepithelial lymphocytes per 100 enterocytes) and collagenous colitis (with a thickened subepithelial collagen band >10µm), respectively. It was reported that the incidence rate of microscope colitis had an upward trend from 4.6 to 24.7 per 100,000 person-year from 2002 to 2011 in Denmark. The median age of microscopic colitis is approximately 65 years at diagnosis, and the incidence is higher in females than males. This disease is rarer in children. Only a few cases have been reported. Here, we reported a case of lymphocytic colitis in an adolescent. This case had a refractory response to the treatment with Budesonide alone and a delayed response after addition of Azathioprine.
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